AMP Molecular in a Minute: Microlearning Modules in Molecular Pathology

Person learning at computer

These bite-sized presentations are designed for a quick review, updates, and educational overviews by experts on a range of topics in molecular pathology.  You can view these on your computer, tablet, or smart-phone to learn something new or to review material for an upcoming seminar, exam, meeting, or journal club.


Please scroll down for a selection of short presentations in different topic areas:

The Molecular Pathology Competency Series

These micro-learning modules are targeted to practicing laboratory professionals and cover many aspects of competency in the laboratory. They are short (10-15 minute) presentations covering Core (basic proficiency) or Advanced (specialized and/or recently updated) concepts in a particular area of laboratory training. This content addresses specific advances in training, technology, and laboratory operations and acts as review and/or updates in important principles for laboratorians over the full arc of their careers.





CORE: Biomarkers for Immunotherapy

This core concept module provides information on the role of microsatellite status, tumor mutational burden levels and PD-L1 expression as biomarkers for immunotherapy of cancer. 

Honey V. Reddi, PhD, FACMG

14 min

ADVANCED: Biomarkers for Immunotherapy

This advanced concept module provides information on the role of microsatellite status, tumor mutational burden levels and PD-L1 expression as biomarkers for immunotherapy of cancer. 

Honey V. Reddi, PhD, FACMG

12 min

CORE: Germline / Somatic Variants

This core concept module covers the question: What are germline variants and somatic variants?

Alanna Church, MD

5 min

ADVANCED: Germline / Somatic Variants

This advanced concept module answers the question: How do we approach the discussion of potential germline variants in tumor-only sequencing?

Alanna Church, MD

7 min

CORE: Lymphoid Clonality Testing

This core concept module reviews the biological basis and clinical utility of lymphoid clonality testing.

Nathan Montgomery, MD PhD

18 min

CORE: Fluorescence in Situ Hybridization (FISH): Methodology and Clinical Utility *NEW*

This core concept module reviews the methodology and clinical utility of fluorescence in situ hybridization (FISH) testing. 

Lori Ramkissoon, MD

13 min

CORE: Fusion Detection by Next Generation Sequencing Using RNA *NEW*

This core concept module will  review the structure of oncogenic gene fusions and the core principles of why and how we use RNA for fusion detection with NGS.

Alanna Church, MD

5 min

CORE: Quantitative PCR *NEW*

This core concept module reviews how PCR can be used to quantify targets using delta Ct, standard curves, or digital PCR.  Here we discuss aspects of each approach.

Lawrence Jennings, MD

25 min

CORE: PCR and Sanger Sequencing *NEW*

This core concept module will review PCR and Sanger Sequencing.

Va Lip

19 min

ADVANCED: Detection of a Cryptic Gene Fusion in a B-ALL *NEW*

This advance concept module will review the utility of targeted RNA sequencing to unravel cryptic gene fusions and how the sequencing results are reviewed, using a case-based approach.

Valentina Nardi, MD

15 min




AMP offers more Microlearning Modules:


Utility of Cell-free DNA in the Clinic: Current State and Future Directions.

Microlearning modules on Liquid Biopsy core concepts and recent advances. These microleanrning modules will cover new topics, advances, and applications for liquid biopsy in the laboratory and in the clinic


Emerging and Evolving Biomarkers Recent Findings, Laboratory Considerations, and Clinical Implications:

Microlearning modules are covered on the most current scientific research (Scientific Underpinings),  laboratory considerations for marker testing approaches (Laboratory Considerations), and on the clinical implications of test results (Clinical Implications). 





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