Emerging and Evolving Biomarkers: Recent Findings, Laboratory Considerations, and Clinical Implications

The extraordinary advancements made over the past several years in the clinical management of cancer have ushered in a new era of optimism for those afflicted with many cancer types. However, these advancements have also created a highly complex environment for healthcare providers and diagnostic laboratory personnel. 

This webinar series will efficiently describe emerging and evolving biomarkers that will be structured to provide a consistent framework for each biomarker. Read more about this series in this JMD article.

Each webinar will feature:

  • scientific15-20 minutes of a scientific overview of recent and relevant research on the biomarker;
  • laboratory15-20 minutes covering the laboratory considerations for the testing approach to each biomarker;
  • clinical15-20 minutes of discussion on the clinical implications of biomarker use.

The recordings will be posted as (1) A complete presentation with pre- and post-tests plus available continuing education credit and (2) A series of short microlearning modules (~15 minute videos) that can be reviewed based on need and interest in the science, laboratory applications, and/or clinical implications of each marker. 



  • Describe the biological principles that underlie the pathogenicity of each biomarker, including the cellular signaling pathways and cellular processes involved.
  • Discuss the appropriate technical approaches and platforms for molecular diagnostic testing for each biomarker.
  • Outline the strengths and limitations of described testing approaches.
  • Apply biomarker information so as to order appropriate testing and interpret biomarker status results within a clinical context.  





Click on the icons below to access the full webinar(s)webinar, the 15-min microlearning module(s) (MLM), or the practice advance paperspaper .

Being eNRGy Conscious: Understanding NRG1 Fusions webinar scientific laboratory clinical  
EGFR Exon 20 Insertions webinar scientific laboratory clinical  
ERBB2 (HER2) in Colorectal Cancer webinar scientific laboratory clinical paper
FLT 3 Mutations and AML webinar scientific laboratory clinical  
HRD Score webinar scientific laboratory clinical  
Immunoglobulin and T-cell Receptor Gene Sequencing webinar scientific laboratory clinical  
KRAS webinar scientific laboratory clinical  
METex14 webinar scientific laboratory clinical paper
Methylation Profiling webinar scientific laboratory clinical  
MGMT webinar scientific laboratory clinical  
Molecular Diagnostic and Clinical Perspectives on MSI Testing for Cancer webinar scientific laboratory clinical  
Mutational Signatures in Cancer webinar scientific laboratory clinical paper
Myeloid Malignancy MRD webinar scientific laboratory clinical  
NTRK webinar scientific laboratory clinical paper
Oncogenic RET Fusions webinar        



Accreditation Statements
AMA PRA Category 1 Credit(s)™
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and Association for Molecular Pathology (AMP). The American Society for Clinical Pathology (ASCP) is accredited by the ACCME to provide continuing medical education for physicians.

The ASCP designates this material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™per webinar. Physicians should claim only credit commensurate with the extent of their participation in the activity.

This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit per webinar. ASCP CMLE credit hours are acceptable for the ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity.



This webinar series on Emerging and Evolving Biomarkers (EEB) is planned and coordinated by the Emerging and Evolving Biomarkers Content Committee:

Anthony N. Snow, MD

Rena Xian, MD (Chair 2024)
The Johns Hopkins School of Medicine

Kurtis D. Davies, PhD

Fei Dong, PMD
Stanford University


Anthony N. Snow, MD

Pawel, Mroz, MD, PhD
University of Minnesota Medical School


Jennifer Bynum, MD

Joanna Conant, MD (T&E Committee Liaison)
University of Vermont Medical Center

And supported by the AMP Training & Education Committee 



Instructions for Accessing Live and On-Demand Webinars from AMP (PDF)




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