Emerging and Evolving Biomarkers: Recent Findings, Laboratory Considerations, and Clinical Implications

The extraordinary advancements made over the past several years in the clinical management of cancer have ushered in a new era of optimism for those afflicted with many cancer types.  However, these advancements have also created a highly complex environment for healthcare providers and diagnostic laboratory personnel.  With the range of clinically informative biomarkers, the types of tests to detect these biomarkers, and the resulting clinical implications constantly expanding and becoming more complex, it has become increasingly burdensome for healthcare professionals to keep pace.

This series will efficiently describe emerging and evolving biomarkers in a series of live webcasts that will be structured to provide a consistent framework in which to consider the application of new information on specific biomarkers. Read more about this series in this JMD article.

Each live webcast will feature:

• 15-20 minutes of a scientific overview of recent and relevant research on the biomarker;
• 15-20 minutes covering the laboratory considerations for the testing approach to each biomarker;
• 15-20 minutes of discussion on the clinical implications of biomarker use.

After broadcast, each webinar will be posted on the AMPED^TM online Learning Management System as 1. A complete presentation with pre- and post-tests plus available continuing education credit and 2. A series of short learning modules that can be reviewed based on need and interest in the science, laboratory applications, and/or clinical implications of each marker. See below for links.

LEARNING OBJECTIVES

• Describe the biological principles that underlie the pathogenicity of each biomarker, including the cellular signaling pathways and cellular processes involved.
• Discuss the appropriate technical approaches and platforms for molecular diagnostic testing for each biomarker.
• Outline the strengths and limitations of described testing approaches.
• Apply biomarker information so as to order appropriate testing and interpret biomarker status results within a clinical context.  
   

SCHEDULE

Webinar #1: MGMT: Updated Perspectives, Laboratory Considerations, and Clinical Implications
Speaker: Tejus Bale, MD, PhD
Recorded: Tuesday June 30th, 2020

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Webinar #2: HRD Score: Updated Perspectives, Laboratory Considerations, and Clinical Implications
Speaker: Melinda Telli, MD
Date: Tuesday July 21st, 2020

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Webinar #3: METex14: Updated Perspectives, Laboratory Considerations, and Clinical Implications
Speaker: Nikoletta Sidiropoulos, MD
Date: Tuesday September 29th, 2020

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View Practice Advance Paper

Webinar #4: NTRK: Updated Perspectives, Laboratory Considerations, and Clinical Implications
Speaker: Lynette M. Sholl, MD
Date: Tuesday December 8th, 2020

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View Practice Advance Paper

Webinar #5: ERBB2 (HER2) in Colorectal Cancer: Recent findings, laboratory considerations, and clinical implications
Speaker: Sinchita Roy-Chowdhuri, MD, PhD
Date: Thursday April 15th, 2021 

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View Practice Advance Paper

Webinar #6: Myeloid Malignancy MRD: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: David Wu, MD, PhD
Date: Tuesday June 29th, 2021 

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Webinar #7: KRAS: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Craig Mackinnon, MD, PhD
Date: Tuesday October 12th, 2021

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Webinar #8: Methylation Profiling: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Brent Orr, MD, PhD
Date: Tuesday January 25th, 2022 at 2:00pm Eastern

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Webinar #9: Immunoglobulin and T-cell receptor gene sequencing: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Rena Xian, MD
Date: Thursday April 7 at 11:00am Eastern

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Webinar #10: Mutational Signatures in Cancer: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Fei Dong, MD
Date: Tuesday May 3 at 1:00pm Eastern

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Webinar #11: Molecular Diagnostic and Clinical Perspectives on Microsatellite Instability Testing for Cancer: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Sameek Roychowdhury, MD, PhD
Date: Thursday, September 22 at 11:00am Eastern

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Webinar # 12: EGFR Exon 20 Insertions: Recent Findings, Laboratory Considerations, and Clinical Implications
Speaker: Eric Vail MD,
Time: Tuesday, December 6, at 1:00pm Eastern

Register
 

Click on the links below to access the full webinar(s) or the 15-min microlearning module(s).

This webinar series on Emerging and Evolving Biomarkers (EEB) is planned and coordinated by the Emerging and Evolving Biomarkers Content Committee:

Lauren L. Ritterhouse, MD, PhD, Content Chair
Massachusetts General Hospital, Harvard Medical School

Kurtis D. Davies, PhD
University of Colorado, Anschutz Medical Campus

Anthony N. Snow, MD
University of Iowa Hospitals and Clinics, Carver College of Medicine

Jennifer Bynum, MD
Northside Hospital

And supported by the AMP Training & Education Committee 

This program has been supported through educational grant funding provided by Amgen and Loxo Oncology at Lilly (for further information concerning Lilly grant funding visit www.lillygrantoffice.com.) Supporting companies had no control over its content. No personally-identifiable information regarding you is provided to any grant supporters.

Instructions for Accessing Live and On-Demand Webinars from AMP (PDF)

AMP is pleased to collaborate in the Immunotherapy Collaborative of Oncology Networked Communities, IC-ONC.  IC-ONC is a global information network in which multidisciplinary healthcare providers, responsible for treating patients with cancer, are connected via education.  

Please be sure to visit www.ic-onc.org to learn more about the collaborative and all it has to offer.