August 2013 Self-Test: AMP Case Report Article in CAP TODAY
A 48-year-old woman with endometrial cancer
- What is the mode of inheritance for Lynch Syndrome?
- Autosomal Dominant
- Autosomal Recessive
- What is the expected IHC pattern associated with a genetic defect in MSH6?
- MSH6(+) / MSH2 (-)
- MSH6(+) / MSH2 (+)
- MSH6 (-) / MSH2 (-)
- MSH6 (-) / MSH2 (+)
- What is the most common cause of Microsatellite instability (MSI) in endometrial carcinoma?
- MLH1 Promoter methylation
- MLH1 Germline mutation
- MSH6 Germline mutation
- PMS2 Germline mutation
ANSWERS to Self-Test for August 2013 Case