AMP 2012 Annual Meeting
October 25 - 27, 2012
Long Beach Convention & Entertainment Center
Long Beach, CA

Long Beach, CA

DEADLINES

Advance Registration - September 24
Hotel Reservations - September 28

EXHIBITOR DEADLINES

Opportunities to exhibit, advertise, and host a corporate workshop still exist.
Contact Catherine Davidge by email at cdavidge@amp.org for more information.

AMP welcomes members of the press to attend the AMP 2012 Annual Meeting. Refer to the formal invitation to the media for more information.
To register as a member of the press, please use the online registration form: http://bit.ly/O5O3WR.


 

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AMP 2012 Annual Meeting

Final Program

Quick Links:

Thursday, October 25

Friday, October 26

Saturday, October 27

PDF of Final Program

Tuesday, October 23, 2012

8:30am - 5:00pm GeT-RM Panel Meeting 2012 (Seperate Registration) [NOT CME]
11:30am - 6:00pm AMP Board Meeting (Invitation Only) [NOT CME]
4:00pm - 7:00pm Attendee, Speaker and Exhibitor Registration and Check-In
6:30pm - 9:00pm Board Dinner (Invitation Only)

Wednesday, October 24, 2012

7:00am - 5:00pm Attendee, Speaker and Exhibitor Registration and Check-In
7:30am - 7:00pm AMP Committee, Interest Group and Working Group Meetings (Separate Schedule)[NOT CME]
8:00am - 5:00pm Corporate Workshops [NOT CME]
7:30am - 8:30am Registration, Continental Breakfast for Outreach Course
8:30am - 3:45pm Molecular Pathology Outreach Course (MPOC) (Separate Registration) (Sponsored by the College of American Pathology. Supported by an unrestricted educational grant from Nanosphere)
7:30pm - 9:30pm Abbott Reception [NOT CME]
6:00pm - 7:00pm MGP Program Directors Meeting (Invitation Only) [NOT CME]

Thursday, October 25, 2012

GENERAL INFORMATION
6:30am - 8:00am Poster Set-Up
7:00am - 6:00pm Attendee, Speaker, and Exhibitor Registration and Check-In
7:00am - 8:00am Continental Breakfast
11:30am - 4:30pm Exhibit Hall Open
     
SCIENTIFIC PROGRAM
7:00am - 8:00am EARLY BIRD SESSIONS
  Molecular Genetics & Infectious Diseases "101"
 

Jean Amos-Wilson, PhD, Berkeley HeartLab, Inc., Alameda, CA

Alexandra Valsamakis, MD, PhD, The Johns Hopkins Medical Institutions, Baltimore, MD

     
8:00am - 8:15am Break
     
8:15am - 8:30am Opening Remarks, AMP Program Committee Chair
  Daniel H. Farkas, PhD, HCLD, Sequenom Center for Molecular Medicine, Grand Rapids, MI
     
8:30am - 9:45am AMP Award for Excellence in Molecular Diagnostics: Presentation and Lecture
  Supported by an unrestricted educational grant from Roche Diagnostics
  Presentation of the Award and Lecture Moderator: Iris Schrijver, MD, Stanford University Medical Center, Stanford, CA
   
  The Molecular Pathology of Pediatric Cancer: Lessons Learned From DNA Sequence Analysis and Their Clincal Implications
  James Downing, MD, St. Jude Children's Research Hospital, Memphis, TN
     
9:45am -10:15am Coffee Break
     
10:15am - 11:45am PLENARY SESSION
  Making the Case for Pharmacogenomics Testing: Integration into a Health Care System
  Supported by an unrestricted educational grant from Roche Diagnostics
    The PREDICT Program at Vanderbilt: Four Drug Interactions and Counting
    Michael Laposata, MD, PhD, Vanderbilt University, Nashville, TN
    Oncology Pharmacogenomics: Identifying Clinically Actionable Targets for Selective Therapeutics in Difficult-to-Treat-Solid Tumors
    John Carpten, PhD, TGEN, Phoenix, AZ
     
11:45am - 12:45pm Concurrent Lunches
   
    General Lunch (Open to all registered attendees) (Supported by Abbott Molecular)
    Trainee Lunch: Pathways to Molecular Training and Practice (Open to all registered trainees)
    International Affairs Working Group Lunch
    Developing a Molecular Pathology Curriculum for Residents
    Strength in Numbers: Molecular Geneticists Meet-and-Greet
   
12:45pm - 2:15pm CONCURRENT WORKSHOPS
   
  BCR-ABL1 and CMV Harmonization: How to Convert to the International Standard?
   
    Converting BCR-ABL1 to the International Scale: Standardizing the Measurement of Relative Gene Expression
    Charles E. Hill, MD, PhD, Emory University Hospital, Atlanta, GA
     
    CMV DNA Harmonization: Can Two Different CMV DNA Standards Bring Order to Chaos?
    Ralf Schoenbrunner, PhD, Life Technologies, Benicia, CA
     
  Interpretation of DNA Sequence Data: The Old and the New
  Supported by an unrestricted educational grant from Illumina
    Clinical Interpretation of Sequence Variation: Challenges Through the Decades
    Elaine Lyon, PhD, ARUP Laboratories, Salt Lake City, UT
    Next Generation Data Only Matters When You Understand the Patient
    Mike Friez, PhD, Greenwood Genetic Center, Greenwood, SC
    Experimental Trials in Translational Genomics are the Pathway to Genomic Medicine
    Robert Green, MD, MPH, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
   
  Thyroid Cancer Diagnostics: From Molecular Lab to Patient's Bedside
    Molecular Diagnostics of Thyroid Cancer: Basic Principles and Laboratory Technique
    Yuri Nikiforov, MD, PhD, University of Pittsburgh Medical Center, Pittsburgh, PA
    Molecular Diagnostics of Thyroid Cancer: Impact on Clinical Practice
    Steven Hodak, MD, University of Pittsburgh Medical Center, Pittsburgh, PA
     
  Lymphoid Clonality Testing: Challenging Cases
    Presenters:
    Rita Braziel, MD, Oregon Health Sciences University, Portland, OR
    Patricia Groenen, PhD, Radboud University Nijmegen Medical Centre, Nijmeen, Gelderland
     
2:15pm - 3:45pm Coffee Break - Visit Exhibit Hall and Posters (Award Applicant Posters Attended)
    Supported by Slone Partners
     
3:45pm - 5:15pm PLENARY SESSION
  Surveillance for the Molecular Laboratory
    Disease Interrogation - Molecular Epidemiologic Studies to Advance Infection Control Strategies
    Barry N. Kreiswirth, PhD, University of Medicine and Dentistry of New Jersey, Newark, NJ
    Informatics Tools for Disease Tracking
    Ari A. Robicsek, MD, Northshore University Healthsystem, Evanston, IL
     
5:15pm - 6:30pm Welcome Reception, Supported by Roche Diagnostics
7:00pm - 9:00pm JMD Editorial Board Meeting
7:00pm - 11:00pm Canadian Member Dinner Meeting
7:00pm - 9:00pm Indian Member Dinner Meeting
   

Friday, October 26, 2012

GENERAL INFORMATION
7:00am - 6:00pm Attendee, Speaker, and Exhibitor Registration and Check-In
7:00am - 8:00am Continental Breakfast, Supported by Hologic | Gen-Probe
9:00am - 4:00pm Exhibit Hall Open
     
SCIENTIFIC PROGRAM
7:00am - 8:00am EARLY BIRD SESSIONS
  Molecular Hematopathology "101"- a great intro for the novice and refresher for the expert
  Janina Longtine, MD, Mount Sinai Medical Center, New York, NY
   
  Solving Challenges in Genomic Testing of FFPE Specimens
    Supported by an unrestricted educational grant from Abbott Molecular
    Tips to Improve RNA Profiling of Paraffin Embedded Tissue
    Margaret L. Gulley, MD, University of North Carolina-Chapel Hill, Chapel Hill, NC
    Mythbusters: Deep Sequencing of DNA and RNA from FFPE Samples
    Toumy Guettouche, PhD, University of Miami Health System, Miami, FL
     
8:00am - 8:15am Break
     
8:15am - 9:45am PLENARY SESSION
  Issues Surrounding Lack of Laboratory Reference Materials: Impact on Assay Development and Validation, QC, and Proficiency Testing
    U.S. Perspective
    Lawrence Jennings, MD, PhD, Children's Memorial Hospital, Chicago, IL
    European Perspective
    David E. Barton, PhD, National Centre for Medical Genetics, Dublin, Ireland
    Addressing Laboratory Reference and Proficiency Testing Material Needs
    Lisa Kalman, PhD, Centers for Disease Control and Prevention, Atlanta, GA
     
9:45am - 10:45am Coffee Break - Visit Exhibit Hall and Posters
  Supported by BioFire Diagnostics
     
10:45am - 11:45am CONCURRENT WORKSHOPS: Platform Presentations of Selected Abstracts
  Abstracts are selected by the Program Committee
   
Platform Presentations of Selected Genetics Abstracts
Supported by an unrestricted educational grant from Illumina
 

[10:49am - 11:02am] G34 - Genetic Testing of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Using Long-Range PCR and Next Generation Sequencing

Hanna Rennert, PhD, Weill Cornell Medical College, New York, NY

   
 

[11:02am - 11:15am] G36 - Validation of X-Inactivation Ratio Analysis Using the AR and SLITRK4 Loci

Kristy Crooks, PhD, University of North Carolina at Chapel Hill, Chapel Hill, NC

   
 

[11:15am - 11:28am] G32 - A Modular Process for the Validation of a Clinical Next Generation Sequencing Pipeline Using HapMap Samples

Martin Powers, MD, Locus Development, San Francisco, CA

   
 

[11:28am - 11:41am] G30 - The Impact of Expanded Next Generation Sequencing Panel Testing for Inherited Cardiomyopathies on Disease Diagnosis: Lessons from the First 500 Cases

Birgit Funke, PhD, Laboratory for Molecular Medicine, Cambridge, MA

   
Platform Presentation of Selected Hematopathology Abstracts
  [10:49am - 11:02am] H12 - Prognostic Significance of Co-Expression of ERG, MN1 and

BAALC Genes By RT-qPCR in Cytogenetically Normal Acute Myeloid Leukemia Specimens

Petr Starostik, MD, Roswell Park Cancer Institute, Buffalo, NY

   
 

[11:02am - 11:15am] H38 - Ultra-Deep Sequencing to Identify Rare Variants within Mutational Hotspots: Application to IGH Diversification in Follicular Lymphoma

Janice Spence, PhD, University of Rochester, Rochester, NY

   
 

[11:15am - 11:28am] H36 - Towards Clinical Use of Next Generation Sequencing to Screen for Mutations in Liquid and Solid Tumors

Robert Daber, PhD, University of Pennsylvania, Philadelphia, PA

   
 

[11:28am - 11:41am] H34 - Comparison of Next Generation Sequencing Platforms for Multi-Gene Mutational Profiling of Hematologic Malignancies in a Clinical Diagnostics Laboratory

Keyur Patel, MD, PhD, The University of Texas M.D. Anderson Cancer Center, Houston, TX

   
Platform Presentation of Selected Infectious Diseases Abstracts
Supported by an unrestricted educational grant from Luminex
 

[10:49am - 11:02am] ID34 - Molecular Characterization of Hepatitis B Virus: A Six Year Follow Up of Genotypes and Subgenotypes Distribution

Roberta Sitnik, PhD, Hospital Israelita Albert Einstein, São Paulo, Brazil

   
 

[11:02am - 11:15am] ID38 - Molecular Characterization of Adenoviruses from Four Outbreaks of Keratoconjunctivitis in New York State in Early 2012

Kirsten St. George, PhD, Wadsworth Center, Albany, NY

   
 

[11:15am - 11:28am] ID36 - The Pulmonary Microbiome in Patients with Cystic Fibrosis: Next Generation Sequencing and Conventional Pathogen Detection

Ruth Ann Luna, PhD, Texas Children's Hospital/Baylor College of Medicine, Houston, TX

   
 

[11:28am - 11:41am] ID26 - Evaluation of Custom Liquid Bead Arrays for the Molecular Detection of Gastrointestinal Pathogens in a Pediatric Population

Renee Webb, BS MT (ASCP), Texas Children's Hospital, Houston, TX

   
Platform Presentation of Selected Solid Tumor Abstracts
Supported by an unrestricted educational grant from Abbott Molecular
 

[10:49am - 11:02am] ST12 - Differential Strand Separation at Critical Temperature Reveals Low-Abundance Mutations in Cancer Samples

Minakshi Guha, PhD, Dana Farber Cancer Institute, Boston, MA

   
 

[11:02am - 11:15am] ST54 - Clinical Next-Generation Sequencing for the Identification of Somatic Mutations in Cancer

Hussam Al-Kateb, MS, PhD, FACMG, Washington University School of Medicine, St. Louis, MO

   
 

[11:15am - 11:28am] ST30 - Challenges in the Interpretation of Cancer Exome Data: A Tiered Strategy to Effectively Report Sequence Variants

Angshumoy Roy, MD, PhD, Baylor College of Medicine, Houston, TX

   
 

[11:28am - 11:41am] ST56 - The Prevalence of FGFR1 Amplification in Lung Squamous Cell Carcinoma as Revealed by FISH Analysis

Lu Wang, MD, PhD, Memorial Sloan-Kettering Cancer Center, New York, NY

     
11:45am - 1:00pm Lunch - Visit Exhibit Hall and View Posters
   
    General Lunch (Open to all registered attendees)
    Supported by Luminex
    What Education Programs Can AMP Offer You?
    Release of the AMP Mutation Nomenclature Database by the Clinical Practice Committee
   
1:00pm - 2:30pm PLENARY SESSION
  Impact of NGS on Molecular Hematopathology
    Next Generation Sequencing of Lymphoid Cancers: Novel Pathogenic Insights and Translational Relevance
    Christian Steidl, MD, British Columbia Cancer Agency, Vancouver, Canada
    Mechanistic Factors That Direct Translocation Formation in Lymphocytes
    Roberto Chiarle, MD, University of Torino, Italy, Torino, Italy
     
2:30pm - 3:30pm Coffee Break - Visit Exhibit Hall and Posters (even-numbered posters attended)
  Supported by Slone Partners
   
3:30pm - 5:00pm CONCURRENT SYMPOSIA
  The Utility of Next Generation Sequencing from a Clinical and Laboratory Perspective
    Whole Genome and Whole Exome Sequencing in the Clinic
    David Bick, MD, Medical College of Wisconsin, Milwaukee, Wisconsin
    Integrating Omics into Medicine
    Michael Snyder, PhD, Stanford University, Stanford, CA
     
  Viral Load Testing and Monitoring Therapeutic Response . Drug Resistance for CMV and Hepatitis C
    Supported by an unrestricted educational grant from Abbott Molecular
    Viral load Testing for Monitoring CMV Disease: Promises Realized and Challenges Remaining
    Aneesh K. Mehta, MD, Emory University School of Medicine, Atlanta, GA
    Role of Molecular Based Testing for Monitoring HCV Therapy in the Era of Highly Effective Direct Acting Anti-Viral Inhibitors
    Mitchell L. Shiffman, MD, Liver Institute of Virginia & Bon Secours Virginia Health System, Richmond, VA
     
5:00pm - 5:15pm Break
   
5:15pm - 6:30pm Business Meeting and Awards Session
6:30pm - 7:30pm Awards Reception, Supported by Hologic | Gen-Probe
7:30pm - 10:30pm Social Event (Ticket Required)

Saturday, October 27, 2012

7:00am - 5:00pm Attendee, Speaker, and Exhibitor Registration and Check-In
7:00am - 8:00am Continental Breakfast, Supported by Focus Diagnostics
9:00am - 1:30pm Exhibit Hall Open
1:00pm - 5:00pm Poster Removal
     
7:00am - 8:00am EARLY BIRD SESSIONS
  Molecular Solid Tumors "101" - a great intro for the novice and refresher for the expert
  Supported by an unrestricted educational grant from Abbott Molecular
  Kevin C. Halling, MD, PhD, Mayo Clinic, Rochester, MN
     
  Economics 101: In-House vs Reference Testing
  Jordan Laser, MD, Hofstra Northshore - LIJ School of Medicine, Manhasset, NY
     
  Review / Update of the Mayo v Prometheus and Gene Patent Court Cases
    Review of the Mayo v Prometheus Court Case
    Joseph M. Colaiano, JD, Mayo Clinic, Rochester, MN
    Update on the Gene Patent Court Case
    Sandra S. Park, JD, American Civil Liberties Union, New York, NY
     
8:00am - 8:15am Break
     
8:15am - 9:45am CONCURRENT SYMPOSIA
  Molecular Testing in Benign Hematology
    Application of Molecular Methods of the Diagnosis of Non-Neoplastic Red Blood Cell Disorders
    James D. Hoyer, MD, Mayo Clinic, Rochester, MN
    Erythrocytosis Syndromes and Red Cell Enzymopathies
    Jennifer L. Oliveira, MD, Mayo Clinic, Rochester, MN
     
  Beyond the Whole Genome: Practical Applications of NGS in Oncology
    Detection of Structural Variation in Target-Enriched NGS
    Eric J. Duncavage, MD, Washington University in St. Louis, St. Louis, MO
    Approaches of the Detection of Low Level Mutations in Cancer Using Sequencing
    G. Michael Makrigiorgos, PhD, Dana Farber Cancer Institute, Boston, MA
     
9:45am - 10:45am Coffee Break - Visit Exhibit Hall and Posters (odd-numbered posters attended)
    Supported by Luminex
     
10:45am - 12:15pm CONCURRENT WORKSHOPS
  Things to Consider When Starting a Molecular Pathology Lab
  Supported by an unrestricted educational grant from Luminex
    Practical Aspects of Validation, Verification and Quality Assurance
    Silvia G. Spitzer, PhD, Stony Brook University Hospital, Stony Brook, NY
    So You Want to Start a Molecular Lab? Things You Should Know
    Gregory J. Tsongalis, PhD, Dartmouth-Hitchcock Medical Center, Lebanon, NH
     
  What to Expect from a New System for Molecular Pathology CPT Coding in 2013
    Implementation of New Molecular Pathology CPT Codes by CMS
    Aaron D. Bossler, MD, PhD, University of Iowa College of Medicine, Iowa City, IA
    The MOLDX Program: Rationale and Experience
    Elaine Jeter, MD, Palmetto GBA, Camden, SC
    Perspectives on Coding and Payment for Molecular Pathology Testing from a Private Payer
    Lee N. Newcomer, MD, United Healthcare Services, Minneapolis, MN
     
  Molecular Diagnostic Testing for Complex Targets
    Supported by an unrestricted educational grant from Luminex
   

Comprehensive Detection of Diarrheal Pathogens: The Next Frontier for Multiplexed Testing

   

Randall T. Hayden, MD, St. Jude Children's Research Hospital, Memphis, TN

   

Metagenomic Medicine Applied to Colitis and Clostridium Difficile

   

James Versalovic, MD, PhD, Texas Children’s Hospital, Houston, TX

     
  Novel Applications of MALDI-TOF Mass Spectromentry
   

Diagnosis and Classification of Amyloidosis by Mass Spectrometry Based Proteomics

   

Ahmet Dogan, MD, PhD, Mayo Clinic, Rochester, MN

   

MADLI-TOF Mass Spectrometry for Microbial Identification

   

Karen Frank, MD, PhD, National Institutes of Health, Bethesda, MD

     
12:15pm - 1:30pm General Lunch (Open to all registered attendees)
     
1:30pm - 3:00pm PLENARY SESSION
  Next Generation Sequencing for Cancer: Whole Genome vs Targeted Approaches
    Clinical Sequencing of Cancer Exomes: The Initial Texas Children's Hospital Experience
    Will Parsons, MD, PhD, Baylor College of Medicine, Houston, TX
    Targeted Next Generation Sequencing for Targeted Therapy: Towards Personalized Oncology
    Marilyn Li, MD, Baylor College of Medicine, Houston, TX
     
3:00pm - 3:15pm Break
     
3:15pm - 4:45pm PLENARY SESSION
  Development and Validation of Next Generation Sequencing in the Clinical Laboratory
    Development and Validation Considerations for Clinical NGS Panel Diagnostics
    Matthew J. Ferber, PhD, Mayo Clinic, Rochester, MN
    Development and Implementation of NG Multi-Gene Sequencing Panels: A Step Toward WES/WGS
    Sherri J. Bale, PhD, GeneDX, Gaithersburg, MD
    Implementing Next-Generation Sequencing-Based Assay for Detecting Somatic Mutations in Clinically Actionable Cancer Genes
   

Shashikant Kulkarni, PhD, Washington University in St. Louis, St. Louis, MO

     
4:45pm - 5:00pm Closing Remarks, AMP Program Committee Chair
  Danial H. Farkas, PhD, HCLD, Sequenom Center for Molecular Medicine, Grand Rapids, MI