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Program
| Tuesday,
November 6, 2007 |
| 12:00pm-5:00pm |
Registration |
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AMP
Council Meeting, (Part I) |
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Wednesday, November 7, 2007 |
| 7:30am-3:30pm |
Pathology Outreach Course, Premier Sponsor: Nanosphere, Inc.
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| 8:00am-5:00pm |
Registration |
| 9:00am-5:00pm |
Corporate Workshops |
| 5:00pm-6:15pm |
MGP
Fellowship Program Directors Meeting |
| 5:45pm-7:45pm |
Abbott Molecular Evening Reception |
| 6:30pm-8:00pm |
AMP
Committee Meetings |
| 8:00pm-9:30pm |
AMP
Strategic Planning Committee Meeting |
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Thursday, November 8, 2007 |
| 7:45am |
Opening Remarks, Karen E. Weck, MD, University of North Carolina
at Chapel Hill, Chapel Hill, NC |
| 8:00am-9:15am |
AMP
AWARD FOR EXCELLENCE IN
MOLECULAR DIAGNOSTICS LECTURE
Janet D. Rowley, MD, University of Chicago, Chicago, IL |
| 9:15am-10:30am |
Break/Visit Exhibits |
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| 10:30am-12:00noon |
PLENARY SESSION I - Genetics |
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Familial Cancer
Moderators: Paul G. Rothberg, PhD, University of Rochester
Medical Center, Rochester, NY and Mary C. Lowery Nordberg, PhD,
Louisiana State University Health Sciences Center, Shreveport,
LA |
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Familial Kidney
Cancer
Jorge R. Toro, MD, National Cancer Institute, Rockville, MD |
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Familial
Pancreatic Cancer
Alison Klein, PhD, Johns Hopkins Medical Institutions,
Baltimore, MD |
| 12:00noon-1:15pm |
Infectious Diseases Subdivision Business Luncheon* |
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Solid Tumors Subdivision Business Luncheon* |
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General Luncheon |
| 1:15pm-2:30pm |
HEMATOPATHOLOGY WORKSHOP I |
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Molecular
Stratification and Targeting of Aggressive B-cell Lymphomas
Moderator: Dan Jones, MD, PhD, UT - MD Anderson Cancer Center,
Houston, TX |
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Genomic
Profiling for Choosing Drug Targets in Large Cell and Mantle
Cell Lymphoma: Focus on p53
Timothy C. Greiner, MD, University of Nebraska Medical Center,
Omaha, NE |
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Identifying New
Targets in Lymphoma: Focus on BCL6
Ari Melnick, MD, Albert Einstein College of Medicine, Bronx, NY |
| 1:15pm-2:30pm |
GENETICS WORKSHOP I
Moderator: Mary C. Lowery Nordberg, PhD, LSU Health Sciences
Center, Shreveport, LA |
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Puzzlers by
Prior
Thomas W. Prior, PhD, Ohio State University, Columbus, OH |
| 2:30pm-4:30pm |
Visit Exhibits & Posters (Odd-numbered posters manned) |
| 4:30pm-5:45pm |
SOLID TUMORS WORKSHOP I
Moderator: Deborah Dillon, MD, Brigham and Women's Hospital,
Boston, MA
CpG Methylation Testing: Clinical Applications in the Evaluation
of Neoplastic Diseases |
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Goals and
Future Projects of the AMP Methylation Working Group
Antonia Sepulveda, MD, PhD, Hospital of the University of
Pennsylvania, Philadelphia, PA |
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Methods of CpG Methylation Testing
Shuji Ogino, MD, PhD, Brigham & Women's Hospital, Boston, MA |
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New and
Alternative Methods for CpG Methylation Testing
Victor V. Levenson, MD, PhD, Northwestern University Cancer
Center, Chicago, IL |
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CpG Methylation
Testing in Colon Cancer-MSI and CIMP Tumor Phenotypes
Wade S. Samowitz, MD, ARUP Laboratories, Salt Lake City, UT |
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CpG Methylation
Testing in Cytological Specimens
Bin Yang, MD, PhD, Cleveland Clinic, Cleveland, OH |
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CpG Methylation
Testing for Cancer Therapy Monitoring
Dan Jones, MD, PhD, UT - MD Anderson
Cancer Center, Houston, TX |
| 4:30pm-5:45pm |
INFECTIOUS
DISEASES WORKSHOP I |
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Bordetella
Pertussis Assays and Standardization
Moderator: Franklin Cockerill III, MD, Mayo Clinic, Rochester,
MN |
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Results of a
Multicenter Study
Gregory J. Tsongalis, PhD, Dartmouth Medical School, Lebanon, NH |
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The Public
Health Perspective
Maria Lucia C. Tondella, PhD, Centers for Disease Control and
Prevention, Atlanta, GA |
| 4:30pm-5:45pm |
TECHNICAL TOPICS WORKSHOP |
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Techniques for
Detection of Gene Copy Number - Beyond Southern Blot
Moderators: Malinda Butz, BS, CLSp (MB), Mayo Clinic, Rochester,
MN
Karen Bijwaard, MS, CLSp (MB), FDA, Rockville, MD |
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Large Gene
Rearrangement Detection by Commercially Available MLPA Assays
Rong Mao, MD, ARUP Laboratories, Salt Lake City, UT |
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Multiplex
Ligation-Dependent Probe Amplification (MLPA): Laboratory
Developed Tests
Patrick Lundquist, BS, CLSp (MB), CLSp (CG), Mayo Clinic,
Rochester, MN |
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Quantitative
Multiplex PCR Analysis for Large Gene Rearrangements
Benjamin Roa, PhD, Myriad Genetics Laboratories, Salt Lake City,
UT |
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Quantitative Microsphere Hybridization
Joan Knoll, PhD, University of Western Ontario, London, Ontario,
CANADA |
| 5:45 pm-7:00pm |
Welcome
Reception Supported by Roche Diagnostics Corporation |
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Friday, November 9, 2007 |
| 7:00am-7:50am |
Early Bird Sessions |
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Validation and Maintenance of ASRs and Lab Developed Assays
Wayne W. Grody, MD, PhD, UCLA School of Medicine, Los Angeles,
CA
Margaret L. Gulley, MD, University of North Carolina at Chapel Hill,
Chapel Hill, NC |
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Mutation
Nomenclature
>>Download Nomenclature Quiz
Shuji Ogino, MD, PhD, Brigham & Women's Hospital, Boston, MA |
| 8:00am-9:30 am |
PLENARY SESSION II: Technical Topics |
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Highly
Multiplexed Molecular Assays
Moderators: Karen Bijwaard, MS, CLSp (MB), FDA, Rockville, MD
Malinda Butz, BS, CLSp (MB), Mayo Clinic, Rochester, MN |
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Highly
Multiplexed Infectious Disease Assays
David R. Hillyard, MD, ARUP Laboratories, Salt Lake City, UT |
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Applications
and Issues with Multiplex Analysis for Genetic and
Hematology/Oncology Assays
Gregory J. Tsongalis, PhD, Dartmouth Medical School, Lebanon, NH
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| 9:30am-10:00am |
Break |
| 10:00am-11:30am |
PLENARY SESSION III: Infectious Diseases |
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Molecular
Testing for Infection Prevention and Therapeutic Guidance
Moderator: Alexandra Valsamakis, MD, PhD, The Johns Hopkins
Medical Institutions, Baltimore, MD |
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Molecular
Testing for Antibiotic Resistance
Lance R. Peterson, MD, Evanston Northwestern Healthcare,
Evanston, IL |
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The Role of the
Virologic Assay in the Management and Treatment of Patients
with Chronic Hepatitis C Virus
Mitchell L. Shiffman, MD, VCU Medical Center, Richmond, VA |
| 11:30am-1:00pm |
Genetics Subdivision Business Luncheon* |
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Hematopathology Subdivision Business Luncheon |
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General Luncheon |
| 1:00pm
- 3:00pm |
Visit Exhibits and Posters
(Even-numbered posters manned) |
| 3:00pm-4:15pm |
HEMATOPATHOLOGY WORKSHOP II |
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Algorithmic
Approaches to the Diagnosis of the Myeloproliferative Disorders
Moderators: Dan Jones, MD, PhD, UT- MD Anderson Cancer Center,
Houston, TX
Lynne V. Abruzzo, MD, PhD, UT- MD Anderson Cancer Center,
Houston, TX |
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Molecular
Algorithms for Diagnosis of Chronic Myeloproliferative Disorders
John Anastasi, MD, University of Chicago, Chicago, IL |
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Platform
Presentations of Selected Hematopathology Abstracts
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H35 |
Quantifying Acquired JAK2 V617F Mutation in Myeloproliferative Disorders
by Real-time
Polymerase Chain Reaction
Scott Reading, PhD, ARUP
Laboratories, Salt Lake City, UT |
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H30 |
JAK2 Mutation Quantification in Myeloproliferative Disorders (MPD);
Correlation
with
Diagnosis and Clinical Parameters
Amanda Wilson, MD, Evanston
Northwestern Healthcare, Evanston, IL |
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H27 |
Targeted Detection of BCR-ABL Kinase Domain
Mutations Using FlexMap
Microspheres and
Luminex Bead Array Technology
Lori A. Frederick, BS, Mayo
Clinic, Rochester, MN |
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H43 |
Ultrafast, High-Throughput
Sequencing-by-Hybridization Assay for Insertion
Mutations in the Nucleophosmin 1 Gene
German Pihan, MD,
Beth
Israel Deaconess Medical Center, Boston, MA |
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| 3:00pm-4:15pm |
INFECTIOUS DISEASES WORKSHOP II |
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Moderator: Alexandra Valsamakis, MD, PhD, The Johns Hopkins
Medical Institutions, Baltimore, MD |
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Platform
Presentations of Selected Infectious Diseases Abstracts |
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ID57 |
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Spread of KPC Carbapenemase-producing K.
pneumoniae to North Florida
Kenneth H. Rand, MD, University of
Florida, Gainesville, FL |
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ID36 |
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Clinical Aspects of HPV Genotyping in
Adolescents
Brandi K. Painter, MD,
Louisiana State University Health
Sciences Center, Shreveport, LA |
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ID59 |
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Using Real-time PCR to Identify
Community-Associated MRSA by Detecting
Panton-Valentine Leukocidin
Suzanne M. Paule, BS, Evanston
Northwestern Healthcare, Evanston, IL |
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ID23 |
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High Prevalence of Multiple Respiratory
Virus Infections Associated with the WU
Polyomavirus
Max Arens, PhD, Washington University,
St. Louis, MO |
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ID17 |
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Use of Web-Based EDCNet and OptiQual
External Positive Controls to Monitor
Quality Performance of User-Defined &
FDA-Approved Assays for Viral Load
Testing
Donna M. Wolk, PhD D(ABMM), University
of Arizona, Tucson, AZ |
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| 4:30pm-6:00pm |
AMP Poster
Reception Supported by Gen-Probe, Inc |
| 6:00pm-7:00pm |
AMP Methylation
Working Group Meeting |
| 7:00pm-10:00pm |
The Journal
of Molecular Diagnostics (JMD) Editorial Board
Meeting Supported by Eragen Biosciences |
| 7:00pm-11:00pm |
Dinner for Canadian AMP Members |
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Saturday, November 10, 2007 |
| 7:00am-7:50am |
Early Bird Sessions |
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Quantitative
Testing for EBV: Diagnostic Issues and Assay Standardization
Moderator: Alexandra Valsamakis, MD, PhD, The Johns Hopkins
Medical Institutions, Baltimore, MD
Margaret L. Gulley, MD, University of North Carolina-Chapel
Hill, Chapel Hill, NC
Randall Hayden, MD, St. Jude Children's Research Hospital,
Memphis, TN
Jutta K. Preiksaitis, MD, ProvLab and University of Alberta,
Edmonton, AB, Canada |
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Overview of
Billable Tests in Solid Tumors
Moderator: William P. Bennett, MD, City of Hope National Medical
Center, Duarte, CA |
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FISH Analysis
of HER2 in Breast Cancer and UroVysionTM for Bladder Cancer
Kevin C. Halling, MD, PhD, Mayo Foundation, Rochester, MN |
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MSI Testing for
Colon Cancer
Jennifer L. Hunt, MD, Cleveland Clinic Foundation, Cleveland, OH |
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1p-19q
Translocation in Oligodendrogliomas
Kathleen M. Murphy, PhD, Johns Hopkins University School of
Medicine, Baltimore, MD |
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Translocations
in Sarcomas
Raymond R. Tubbs, DO, Cleveland Clinic Foundation,
Cleveland, OH |
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c-Kit
Alterations in GISTs
Christopher L. Corless, MD, PhD, Oregon Health Sciences
University, Portland, OR |
| 8:00am-9:30am |
PLENARY SESSION IV: Hematopathology |
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New Insights
into Leukemia and Lymphoma
Moderator: Lynne V. Abruzzo, MD, PhD, UT-MD Anderson Cancer
Center, Houston, TX |
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DNA Double
Strand Breaks, Translocations, and Lymphoma
Frederick W. Alt, PhD, Harvard University, Boston, MA |
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Cancer Stem
Cells: Diagnostic and Therapeutic Challenges
Catriona Jamieson, MD, PhD, UCSD
Medical Center, La Jolla, CA |
| 9:30am-10:00am |
Break |
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10:00am-11:30am |
PLENARY SESSION V: Solid Tumors |
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Novel Molecular
Biomarkers for Solid Tumors
Moderator: Deborah Dillon, MD, Brigham and Women's Hospital,
Boston, MA |
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Genetic
Variation at 8q24 and Cancer Risk
Christopher Haiman, PhD, University of Southern California, Los
Angeles, CA |
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TMPRSS2-ERG
Fusion Prostate Cancer: A Distinct Subclass with Clinical
Implications
Mark Rubin, MD, Weill Cornell Medical College, New York, NY |
| 11:30am-12:30pm |
General
Luncheon |
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Trainee
Luncheon |
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Career Paths
for Molecular Pathologists in Both Academia and Other Settings
Daniel H. Farkas, PhD, HCLD, Center for Molecular Medicine,
Grand Rapids, MI
Jeffrey A. Kant, MD, PhD, University of Pittsburgh Medical
Center, Pittsburgh, PA
Debra G. B. Leonard, MD, PhD, New York Presbyterian Hospital,
New York, NY
Janina A. Longtine, MD, Brigham & Women's Hospital, Boston, MA
Ted E. Schutzbank, PhD, CompuNET CLinical Laboratories, Moraine,
OH |
| 12:45pm-2:00pm
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SOLID TUMORS WORKSHOP II |
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Gene Expression
Testing in Breast Cancer - Panel Discussion
Moderator: William P. Bennett, MD, City of Hope National Medical
Center, Duarte, CA
Philip Bernard, MD, University of Utah, Salt Lake City, UT
Mark G. Erlander, PhD, AviaraDx, Inc, Carlsbad, CA
Steven Shak, MD, Genomic Health, Inc., Redwood City, CA
W. Fraser Symmans, MD, UT-MD Anderson Cancer Center, Houston, TX |
| 12:45pm-2:00pm
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GENETICS WORKSHOP II |
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Pharmacogenetics of Warfarin Therapy
Moderator: Paul G. Rothberg, PhD, University of Rochester
Medical Center, Rochester, NY |
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Pharmacogenetics and
www.warfarindosing.com
Brian F. Gage, MD, Washington University School of Medicine, St.
Louis, MO |
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Panel
Discussion: Implementation of a Program to Aid in Warfarin
Dosing
Rana Domiati-Saad, PhD, Baylor University Medical Center,
Dallas, TX
Brian F. Gage, MD, Washington University School of Medicine, St.
Louis, MO
Mary Lowery Nordberg, PhD, LSU Health
Sciences Center, Shreveport, LA
Gregory J. Tsongalis, PhD, Dartmouth Medical School, Lebanon, NH
Karen E. Weck, MD, University of North Carolina at Chapel Hill,
Chapel Hill, NC |
| 2:15pm- 3:45pm |
SPECIAL TOPICS WORKSHOP |
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Molecular Meat
and Potatoes: Reimbursement and Regulatory Issues
Moderator: Karen E. Weck, MD, University of North Carolina at
Chapel Hill, Chapel Hill, NC |
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Coding
Conundrums: The AMPire Strikes Back
Jeffrey A. Kant, MD, PhD, University of Pittsburgh Medical
Center, Pittsburgh, PA |
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Legislative &
Regulatory Issues Update
Andrea Ferreira-Gonzalez, PhD, Virginia Commonwealth University,
Richmond, VA
Debra G. B. Leonard, MD, PhD, New York Presbyterian Hospital,
New York, NY |
| 4:00pm-5:15pm |
Business Meeting/Awards Presentation/Closing Remarks |
| 5:15pm-6:30pm |
Awards Reception Supported by Third Wave Technologies |
| 6:30pm- 9:30pm |
AMP
Council Meeting (Part II) |
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*Seating is limited and therefore by pre-registration ticket
only. |
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